Research

Alzheimer's 101

Overview

Alzheimer’s Disease (AD) is a brain disease that progressively destroys memory and thinking skills, eventually affecting the ability to perform simple daily tasks.

It is the most common cause of dementia, accounting for 60% to 80% of cases. It is characterized by the presence of amyloid plaques (clumps of protein between brain cells) and tau tangles (twisted fibers inside brain cells), which disrupt communication between neurons and lead to cell death.

Core Concepts

01

Dementia is a general term for cognitive decline; Alzheimer’s is a specific disease and the most common cause of dementia.

02

Alzheimer’s involves amyloid plaques (between cells) and tau tangles (inside cells), leading to neuron damage.

03

Aging is the greatest risk factor, but Alzheimer’s is not a normal part of aging.

04

Symptoms develop gradually and worsen over 4 to 20 years.

Diagnostics

Blood-Based Biomarkers

PET Imaging

Treatment Strategies

FDA-Approved Therapies

Monoclonal antibody infusions targeting amyloid plaques

Investigational Approaches

Lifestyle Approaches

Regular physical and cognitive activity

Mediterranean or MIND diet
Nutrients such as Vitamin C and D3

Treating Symptoms

Cholinergic medications for memory support

Therapies targeting agitation and mood without worsening cognition